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Chiltern Railways is advising customers not to travel on its services on Sunday 14 and Monday 15 January.
Due to recent heavy rainfall, a landslip occurred on Thursday 11 January on the Chiltern main line between Bicester North and Haddenham & Thame Parkway.
The line has been partially blocked, meaning that fewer services have been able to run on the one track available since the disruption began.
The line between Bicester North and Haddenham & Thame Parkway will be fully closed on Sunday 14 January and Monday 15 January. This means that no trains will be able run through the area.